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Plasma Membrane Calcium-Transporting ATPase 4 (ATP2B4) Antibody
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Catalogue No: abx028119
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].
Research Articles on Plasma Membrane Calcium-Transporting ATPase 4 (ATP2B4)
| Target | Plasma Membrane Calcium-Transporting ATPase 4 (ATP2B4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1174-1202 amino acids from the C-terminal region of human ATP2B4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P23634 (UniProt, ExPASy) |
| UniProt Secondary AC | B1APW5, B1APW6, Q13450, Q13452, Q13455, Q16817, Q7Z3S1 |
| UniProt Entry Name | AT2B4_HUMAN |
| Gene Symbol | ATP2B4 |
| KEGG | hsa:493 |
| String | 9606.ENSP00000350310 |
| Molecular Weight | Calculated MW: 138 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |