V-Type Proton ATPase Subunit B, Brain Isoform (ATP6V1B2) Antibody
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Catalogue No: abx002706
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(Size: 20 µl)
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Datasheet SDS
ATP6V1B2 Antibody is a Rabbit Polyclonal antibody against ATP6V1B2. This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
Research Articles on V-Type Proton ATPase Subunit B, Brain Isoform (ATP6V1B2)
| Target | V-Type Proton ATPase Subunit B, Brain Isoform (ATP6V1B2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to ATP6V1B2. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P21281 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5Z3, D3DSQ5, Q14544, Q15859, Q96IR0 |
| UniProt Entry Name | VATB2_HUMAN |
| Gene Symbol | ATP6V1B2 |
| GeneID | 526 |
| OMIM | 124480 |
| NCBI Accession | NP_001684.2 |
| HGNC | 854 |
| KEGG | hsa:526 |
| Ensembl | ENSG00000147416 |
| String | 9606.ENSP00000276390 |
| Molecular Weight | Calculated MW: 57 kDa Observed MW: 57 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |