V-Type Proton ATPase Subunit E 1 (ATP6V1E1) Antibody

ATP6V1E1 Antibody is a Rabbit Polyclonal antibody against ATP6V1E1. This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.

Target	V-Type Proton ATPase Subunit E 1 (ATP6V1E1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 77-226 of human ATP6V1E1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P36543 (UniProt, ExPASy)
UniProt Secondary AC	A8MUE4, A8MUN4
UniProt Entry Name	VATE1_HUMAN
Gene Symbol	ATP6V1E1
GeneID	529
NCBI Accession	NP_001687.1
KEGG	hsa:529
String	9606.ENSP00000253413
Molecular Weight	Calculated MW: 26 kDa Observed MW: 31 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on V-Type Proton ATPase Subunit E 1 (ATP6V1E1)

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