V-Type Proton ATPase Subunit F (ATP6V1F) Antibody

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein.

Target	V-Type Proton ATPase Subunit F (ATP6V1F)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 82-111 amino acids from the C-terminal region of human ATP6V1F.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16864 (UniProt, ExPASy)
UniProt Secondary AC	C9J2K4, Q6IBA8
UniProt Entry Name	VATF_HUMAN
Gene Symbol	ATP6V1F
GeneID	9296
OMIM	607160
HGNC	16832
KEGG	hsa:9296
Ensembl	ENSG00000128524
Molecular Weight	Calculated MW: 13.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow ATP6V1F.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on V-Type Proton ATPase Subunit F (ATP6V1F)

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