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ATPase, Cu++ Transporting Beta Polypeptide (ATP7B) Antibody
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Catalogue No: abx004341
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US$217.50
(Size: 20 µl)
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Datasheet SDS
ATP7B Antibody is a Rabbit Polyclonal antibody against ATP7B. This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
Research Articles on ATPase, Cu++ Transporting Beta Polypeptide (ATP7B)
| Target | ATPase, Cu++ Transporting Beta Polypeptide (ATP7B) |
| Research Area | Signal Transduction |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/1000 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to ATP7B. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35670 (UniProt, ExPASy) |
| UniProt Secondary AC | Q16318, Q16319, Q4U3V3, Q59FJ9, Q5T7X7 |
| UniProt Entry Name | ATP7B_HUMAN |
| Gene Symbol | ATP7B |
| GeneID | 540 |
| NCBI Accession | NP_001230111.1 |
| KEGG | hsa:540 |
| String | 9606.ENSP00000242839 |
| Molecular Weight | Calculated MW: 157 kDa Observed MW: 157 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |