Aurora Kinase A (AURKA) Antibody
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Catalogue No: abx011734
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Research Articles on Aurora Kinase A (AURKA)
| Target | Aurora Kinase A (AURKA) |
| Research Area | Enzymes and Kinases |
| Clonality | Monoclonal |
| Reactivity | Human, Monkey, Rat |
| Tested Applications | ELISA, WB, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human AURKA expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O14965 (UniProt, ExPASy) |
| UniProt Secondary AC | E1P5F9, O60445, O75873, Q9BQD6, Q9UPG5 |
| UniProt Entry Name | AURKA_HUMAN |
| Gene Symbol | AURKA |
| GeneID | 6790 |
| OMIM | 603072 |
| HGNC | 11393 |
| KEGG | hsa:6790 |
| Ensembl | ENSG00000087586 |
| String | 9606.ENSP00000216911 |
| Enzyme Commission Number | EC 2.7.11.1 |
| Molecular Weight | 48 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |




