Aurora Kinase A (AURKA) Antibody

Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation.Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal.Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen.Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.

Target	Aurora Kinase A (AURKA)
Clonality	Monoclonal
Reactivity	Human, Monkey, Rat
Tested Applications	ELISA, WB, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human AURKA expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
GeneID	6790
Molecular Weight	48 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aurora Kinase A (AURKA)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue