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Aurora Kinase A (AURKA) Antibody
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Catalogue No: abx015773
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US$427.75
(Size: 100 µl)
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Datasheet SDS
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation.Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal.Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen.Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
Research Articles on Aurora Kinase A (AURKA)
| Target | Aurora Kinase A (AURKA) |
| Research Area | Enzymes and Kinases |
| Clonality | Monoclonal |
| Reactivity | Human, Monkey, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human AURKA expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O14965 (UniProt, ExPASy) |
| UniProt Secondary AC | E1P5F9, O60445, O75873, Q9BQD6, Q9UPG5 |
| UniProt Entry Name | AURKA_HUMAN |
| Gene Symbol | AURKA |
| GeneID | 6790 |
| OMIM | 603072 |
| HGNC | 11393 |
| KEGG | hsa:6790 |
| Ensembl | ENSG00000087586 |
| String | 9606.ENSP00000216911 |
| Molecular Weight | 48 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |