Beta-2-Microglobulin (B2M) Antibody

B2M Antibody is a Rabbit Polyclonal antibody against B2M. This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

Target	Beta-2-Microglobulin (B2M)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 21-119 of human beta 2 Microglobulin.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P61769 (UniProt, ExPASy)
UniProt Secondary AC	P01884, Q540F8, Q6IAT8, Q9UCK0, Q9UD48, Q9UDF4
UniProt Entry Name	B2MG_HUMAN
Gene Symbol	B2M
GeneID	567
NCBI Accession	NP_004039.1
KEGG	hsa:567
String	9606.ENSP00000452780
Molecular Weight	Calculated MW: 14 kDa Observed MW: 12 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Beta-2-Microglobulin (B2M)

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