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Beta-1,4-Galactosyltransferase 2 (B4GALT2) Antibody
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Catalogue No: abx034385
Price:
US$326.25
(Size: 80 µl)
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B4GALT2 is one of type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1, 4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue.
Research Articles on Beta-1,4-Galactosyltransferase 2 (B4GALT2)
| Target | Beta-1,4-Galactosyltransferase 2 (B4GALT2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 290-318 amino acids from the C-terminal region of human B4GALT2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60909 (UniProt, ExPASy) |
| UniProt Entry Name | B4GT2_HUMAN |
| Gene Symbol | B4GALT2 |
| KEGG | hsa:8704 |
| String | 9606.ENSP00000310696 |
| Molecular Weight | Calculated MW: 42 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Hamster B4GALT2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |