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| Target | Beta-Secretase 1 (BACE1) |
| Research Area | Signal Transduction |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fragment corresponding to 169-403 AA of human BACE1. |
| Isotype | IgG |
| Form | Lyophilized |
| Purification | Purified by Protein A/G column chromatography. |
| Reconstitution | Reconstitute in 100 µl of sterile distilled H2O with 50% glycerol. |
| Storage | Store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P56817 (UniProt, ExPASy) |
| UniProt Secondary AC | A0M8W7, B0YIU9, E9PE65, H7BXJ9, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5, Q9ULS1 |
| UniProt Entry Name | BACE1_HUMAN |
| Gene Symbol | BACE1 |
| GeneID | 23621 |
| OMIM | 604252 |
| NCBI Accession | NM_012104 |
| HGNC | 933 |
| KEGG | hsa:23621 |
| Ensembl | ENSG00000186318 |
| String | 9606.ENSP00000318585 |
| Molecular Weight | Observed MW: 56 kDa |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Specificity | Predicted to react with Mouse and Rat BACE1. |
| Concentration | Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Availability | Shipped within 7-15 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |