Bcl2-Associated Agonist Of Cell Death (BAD) Antibody

BAD Antibody is a Rabbit Polyclonal antibody against BAD. The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Target	Bcl2-Associated Agonist Of Cell Death (BAD)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Bad.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92934 (UniProt, ExPASy)
UniProt Secondary AC	O14803, Q6FH21
UniProt Entry Name	BAD_HUMAN
Gene Symbol	BAD
GeneID	572
NCBI Accession	NP_004313.1
KEGG	hsa:572
String	9606.ENSP00000378040
Molecular Weight	Calculated MW: 18 kDa Observed MW: 15 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Bcl2-Associated Agonist Of Cell Death (BAD)

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