B-Cell Lymphoma/leukemia 10 (BCL10) Antibody

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Catalogue No: abx015774
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
Bcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN.Entrez Protein NP_003912.It is a protein containing a caspase recruitment domain (CARD).It plays an important role in apoptosis and activating NF-kappaB.The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling.Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma.MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.

Target B-Cell Lymphoma/leukemia 10 (BCL10)
Clonality Monoclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC, IF/ICC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human BCL-10 expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
GeneID 8915
Molecular Weight 26 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on B-Cell Lymphoma/leukemia 10 (BCL10)


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