Bcl2-Related protein A1 (BCL2A1) Antibody

BCL2A1 Antibody is a Rabbit Polyclonal antibody against BCL2A1. This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target	Bcl2-Related protein A1 (BCL2A1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 70-150 of human BCL2A1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16548 (UniProt, ExPASy)
UniProt Secondary AC	Q6FGZ4, Q6FH19, Q86W13, Q99524
UniProt Entry Name	B2LA1_HUMAN
Gene Symbol	BCL2A1
GeneID	597
NCBI Accession	NP_004040.1
KEGG	hsa:597
String	9606.ENSP00000267953
Molecular Weight	Calculated MW: 20 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Bcl2-Related protein A1 (BCL2A1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue