Bcl-2-Like Protein 1 (BCL2L1) Antibody
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Catalogue No: abx034903
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US$326.25
(Size: 80 µl)
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Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X (S) promotes apoptosis.
Research Articles on Bcl-2-Like Protein 1 (BCL2L1)
| Target | Bcl-2-Like Protein 1 (BCL2L1) |
| Research Area | Immunology |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified His-tagged Human BCL2L1 protein |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q07817 (UniProt, ExPASy) |
| UniProt Secondary AC | E1P5L6, Q5CZ89, Q5TE65, Q92976 |
| UniProt Entry Name | B2CL1_HUMAN |
| NCBI Accession | NP_001182.1 NP_612815.1 |
| KEGG | hsa:598 |
| String | 9606.ENSP00000302564 |
| Molecular Weight | Calculated MW: 26 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |