Bcl-2-Like Protein 1 (BCL2L1) Antibody

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Catalogue No: abx000597
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
BCL2L1 Antibody is a Rabbit Polyclonal antibody against BCL2L1. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq].

Target Bcl-2-Like Protein 1 (BCL2L1)
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human Bcl-XL.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q07817 (UniProt, ExPASy)
UniProt Secondary AC E1P5L6, Q5CZ89, Q5TE65, Q92976
UniProt Entry Name B2CL1_HUMAN
Gene Symbol BCL2L1
GeneID 598
NCBI Accession NP_001304848.1
KEGG hsa:598
String 9606.ENSP00000302564
Molecular Weight Calculated MW: 26 kDa
Observed MW: 30 kDa
Buffer PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Bcl-2-Like Protein 1 (BCL2L1)


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