Bcl2 Like Protein 11 (BCL2L11) Antibody
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Catalogue No: abx000675
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US$348.00
(Size: 60 µl)
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Datasheet SDS
BCL2L11 Antibody is a Rabbit Polyclonal antibody against BCL2L11. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
Research Articles on Bcl2 Like Protein 11 (BCL2L11)
| Target | Bcl2 Like Protein 11 (BCL2L11) |
| Research Area | Infection Immunity |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human Bim |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O43521 (UniProt, ExPASy) |
| UniProt Entry Name | B2L11_HUMAN |
| Gene Symbol | BCL2L11 |
| GeneID | 10018 |
| NCBI Accession | NP_619527.1 |
| KEGG | hsa:10018 |
| String | 9606.ENSP00000376943 |
| Molecular Weight | Calculated MW: 4-22 kDa Observed MW: 18 kDa/23 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
