Brain-Expressed Protein Associating With Nedd4 Homolog (BEAN) Antibody

The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA) n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target	Brain-Expressed Protein Associating With Nedd4 Homolog (BEAN)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human BEAN.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q3B7T3 (UniProt, ExPASy)
UniProt Secondary AC	B3KPC0, H3BP97
UniProt Entry Name	BEAN1_HUMAN
KEGG	hsa:146227
String	9606.ENSP00000442793
Molecular Weight	Calculated MW: 28.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Brain-Expressed Protein Associating With Nedd4 Homolog (BEAN)

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