Beta-Adrenergic Receptor Kinase 2 (GRK3) Antibody
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Catalogue No: abx033110
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the ADRBK2 enzyme, also known as GRK3, has 85% amino acid similarity with ADRBK1, with the protein kinase catalytic domain having 95% similarity. The ADRBK2 mRNA is approximately 8 kilobases with a distribution similar to that of ADRBK1. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
Research Articles on Beta-Adrenergic Receptor Kinase 2 (GRK3)
| Target | Beta-Adrenergic Receptor Kinase 2 (GRK3) |
| Research Area | Endocrinology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Monkey |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 633-660 amino acids from the C-terminal region of human AD_K2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35626 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9UGW9 |
| UniProt Entry Name | ARBK2_HUMAN |
| NCBI Accession | NP_005151.2 |
| KEGG | hsa:157 |
| String | 9606.ENSP00000317578 |
| Molecular Weight | Calculated MW: 79.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |