BH3-Interacting Domain Death Agonist (BID) Antibody

BID Antibody is a Rabbit Polyclonal antibody against BID. This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Target	BH3-Interacting Domain Death Agonist (BID)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human Bid.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P55957 (UniProt, ExPASy)
UniProt Secondary AC	Q549M7, Q71T04, Q7Z4M9, Q8IY86
Gene Symbol	BID
GeneID	637
NCBI Accession	NP_001187.1
Molecular Weight	Calculated MW: 22 kDa Observed MW: 20/15 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on BH3-Interacting Domain Death Agonist (BID)

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