Menu

Myc Box-Dependent-Interacting Protein 1 (BIN1) Antibody

Catalogue No: abx001484
Price: £120.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Myc Box-Dependent-Interacting Protein 1 (BIN1) Antibody Myc Box-Dependent-Interacting Protein 1 (BIN1) Antibody Myc Box-Dependent-Interacting Protein 1 (BIN1) Antibody Myc Box-Dependent-Interacting Protein 1 (BIN1) Antibody Myc Box-Dependent-Interacting Protein 1 (BIN1) Antibody

Available Options

* Size:




BIN1 Antibody is a Rabbit Polyclonal antibody against BIN1. This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

Target BIN1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human BIN1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O00499 (UniProt, ExPASy)
UniProt Entry Name BIN1_HUMAN
Gene Symbol BIN1
GeneID 274
KEGG hsa:274
String 9606.ENSP00000316779
Molecular Weight Calculated MW: 45-64 kDa
Observed MW: 65 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Myc Box-Dependent-Interacting Protein 1 (BIN1) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good


Tags:
(Click to show)