Tyrosine-Protein Kinase BLK (BLK) Antibody
REQUEST MORE INFO
Catalogue No: abx010468
Price:
US$427.75
(Size: 100 µl)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development. Activation of B cells by various ligands is accompanied by activation of Blk. It has been suggested that Blk is involved in the control of B cell differentiation and proliferation. Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis. Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response.
Research Articles on Tyrosine-Protein Kinase BLK (BLK)
| Target | Tyrosine-Protein Kinase BLK (BLK) |
| Research Area | Enzymes and Kinases |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of BLK expressed in E. coli. |
| Isotype | IgG2a |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P51451 (UniProt, ExPASy) |
| UniProt Secondary AC | Q16291, Q96IN1 |
| UniProt Entry Name | BLK_HUMAN |
| Gene Symbol | BLK |
| GeneID | 640 |
| OMIM | 191305 |
| HGNC | 1057 |
| KEGG | hsa:640 |
| Ensembl | ENSG00000136573 |
| String | 9606.ENSP00000259089 |
| Enzyme Commission Number | EC 2.7.10.2 |
| Molecular Weight | 58 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |