Polycomb Complex Protein BMI-1 (BMI1) Antibody
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Catalogue No: abx010585
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US$427.75
(Size: 100 µl)
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Datasheet SDS
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Research Articles on Polycomb Complex Protein BMI-1 (BMI1)
| Target | Polycomb Complex Protein BMI-1 (BMI1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human BMI1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35226 (UniProt, ExPASy) |
| UniProt Secondary AC | Q16030, Q5T8Z3, Q96F37 |
| UniProt Entry Name | BMI1_HUMAN |
| Gene Symbol | BMI1 |
| GeneID | 648 |
| OMIM | 164831 |
| HGNC | 1066 |
| KEGG | hsa:100532731 hsa:648 |
| Ensembl | ENSG00000168283 |
| String | 9606.ENSP00000473391 |
| Molecular Weight | 37 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |