Polycomb Complex Protein BMI-1 (BMI1) Antibody
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Catalogue No: abx034091
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Polycomb Complex Protein BMI-1 (BMI1) Antibody is a Rabbit polyclonal against Polycomb Complex Protein BMI-1 (BMI1). Polycomb Complex Protein BMI-1 (BMI1) is a component of the Polycomb group (PcG) multiprotein PRC1 complex, which transcription repression of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Research Articles on Polycomb Complex Protein BMI-1 (BMI1)
| Target | Polycomb Complex Protein BMI-1 (BMI1) |
| Research Area | Signal Transduction |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/8000, IHC-P: 1/10 - 1/50, IF/ICC: 1/25, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant Polycomb Complex Protein BMI-1 (BMI1). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35226 (UniProt, ExPASy) |
| UniProt Secondary AC | Q16030, Q5T8Z3, Q96F37 |
| UniProt Entry Name | BMI1_HUMAN |
| Gene Symbol | BMI1 |
| KEGG | hsa:100532731 hsa:648 |
| String | 9606.ENSP00000473391 |
| Molecular Weight | Calculated MW: 37 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Concentration | 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |