Bone Morphogenetic Protein Receptor 1A (BMPR1A) Antibody

BMPR1A Antibody is a Rabbit Polyclonal antibody against BMPR1A. The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Target	Bone Morphogenetic Protein Receptor 1A (BMPR1A)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 24-200 of human BMPR1A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P36894 (UniProt, ExPASy)
UniProt Secondary AC	A8K6U9, Q8NEN8
UniProt Entry Name	BMR1A_HUMAN
Gene Symbol	BMPR1A
GeneID	657
NCBI Accession	NP_004320.2
KEGG	hsa:657
String	9606.ENSP00000361107
Molecular Weight	Calculated MW: 60 kDa Observed MW: 60 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Bone Morphogenetic Protein Receptor 1A (BMPR1A)

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