Bone Morphogenetic Protein Receptor 1B (BMPR1B) Antibody
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Catalogue No: abx001630
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US$348.00
(Size: 60 µl)
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Datasheet SDS
BMPR1B Antibody is a Rabbit Polyclonal antibody against BMPR1B. This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
Research Articles on Bone Morphogenetic Protein Receptor 1B (BMPR1B)
| Target | Bone Morphogenetic Protein Receptor 1B (BMPR1B) |
| Research Area | Developmental Science, Bone Metabolism |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human BMPR1B |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O00238 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R953, B4DSV1, P78366 |
| UniProt Entry Name | BMR1B_HUMAN |
| Gene Symbol | BMPR1B |
| GeneID | 658 |
| NCBI Accession | NP_001194.1 |
| KEGG | hsa:658 |
| String | 9606.ENSP00000401907 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
