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Bone Morphogenetic Protein Receptor 1B (BMPR1B) Antibody

Catalogue No: abx001630
Price: £120.00
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Bone Morphogenetic Protein Receptor 1B (BMPR1B) Antibody Bone Morphogenetic Protein Receptor 1B (BMPR1B) Antibody Bone Morphogenetic Protein Receptor 1B (BMPR1B) Antibody

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BMPR1B Antibody is a Rabbit Polyclonal antibody against BMPR1B. This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

Target BMPR1B
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human BMPR1B.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O00238 (UniProt, ExPASy)
UniProt Secondary AC B2R953, B4DSV1, P78366
UniProt Entry Name BMR1B_HUMAN
Gene Symbol BMPR1B
GeneID 658
KEGG hsa:658
String 9606.ENSP00000401907
Molecular Weight Calculated MW: 56 kDa, 60 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Bone Morphogenetic Protein Receptor 1B (BMPR1B) Antibody

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