Natriuretic Peptides B (NPPB) Antibody

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Catalogue No: abx016077
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
Natriuretic Peptides B (NPPB) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin.ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain.BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties.It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload.These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues.This ring structure shows high homology between different natriuretic.

Target Natriuretic Peptides B (NPPB)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, IHC
Host Mouse
Recommended dilutions ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic peptide corresponding to aa (Gly-Leu-Gln-Glu-Gln-Arg-Asn-His-Leu-Gln-Gly-Lys-Leu-Cys) of human BNP, conjugated to KLH.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16860 (UniProt, ExPASy)
UniProt Secondary AC B0ZBE9, Q6FGY0, Q9P2Q7
UniProt Entry Name ANFB_HUMAN
Gene Symbol NPPB
GeneID 4879
OMIM 600295
HGNC 7940
KEGG hsa:4879
Ensembl ENSG00000120937
String 9606.ENSP00000365651
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Natriuretic Peptides B (NPPB)


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