BTD Antibody is a Rabbit Polyclonal antibody against BTD. The protein encoded by this gene functions to recycle protein-bound biotin by cleaving biocytin (biotin-epsilon-lysine), a normal product of carboxylase degradation, resulting in regeneration of free biotin. The encoded protein has also been shown to have biotinyl transferase activity. Mutations in this gene are associated with biotinidase deficiency. Multiple transcript variants encoding different isoforms have been described.

Target	Biotinidase (BTD)
Research Area	Enzymes and Kinases
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	IHC
Host	Rabbit
Recommended dilutions	IHC-P: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein corresponding to human BTD
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Shelf Life	12 months.
UniProt Primary AC	P43251 (UniProt, ExPASy)
UniProt Secondary AC	A6NHF2, B2R865, B4DFX1, B4DLJ9, B7Z7C9, F8W1Q3, Q96EM9
UniProt Entry Name	BTD_HUMAN
Gene Symbol	BTD
GeneID	686
NCBI Accession	NP_000051.1
KEGG	hsa:686
String	9606.ENSP00000400995
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Biotinidase (BTD)

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