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Tyrosine-Protein Kinase BTK (BTK) Antibody
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Catalogue No: abx001327
Price:
US$203.00
(Size: 20 µl)
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BTK Antibody is a Rabbit Polyclonal antibody against BTK. The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Tyrosine-Protein Kinase BTK (BTK)
| Target | Tyrosine-Protein Kinase BTK (BTK) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human BTK. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q06187 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RAW1, Q32ML5 |
| UniProt Entry Name | BTK_HUMAN |
| Gene Symbol | BTK |
| GeneID | 695 |
| NCBI Accession | NP_000052.1 |
| KEGG | hsa:695 |
| String | 9606.ENSP00000483570 |
| Molecular Weight | Calculated MW: 76 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
