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Btk (pY223) Antibody

Catalogue No: abx000168
Price: £120.00
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Btk (pY223) Antibody is a Rabbit Polyclonal antibody against Btk (pY223). The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target Btk (pY223)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y223 of human Btk.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q06187 (UniProt, ExPASy)
UniProt Secondary AC B2RAW1, Q32ML5
UniProt Entry Name BTK_HUMAN
Gene Symbol BTK
GeneID 695
KEGG hsa:69
String 9606.ENSP00000483570
Molecular Weight Calculated MW: 76 kDa, 79 kDa
Observed MW: Refer to Figures
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Btk (pY223) Antibody

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