Btk (pY223) Antibody

Btk (pY223) Antibody is a Rabbit Polyclonal antibody against Btk (pY223). The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target	Btk (pY223)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around Y223 of human Btk.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q06187 (UniProt, ExPASy)
UniProt Secondary AC	B2RAW1, Q32ML5
UniProt Entry Name	BTK_HUMAN
Gene Symbol	BTK
GeneID	695
NCBI Accession	NP_000052.1
KEGG	hsa:695
String	9606.ENSP00000483570
Molecular Weight	Calculated MW: 76 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Btk (pY223)

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