Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 (BUB1) Antibody
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Catalogue No: abx033844
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.
Research Articles on Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 (BUB1)
| Target | Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 (BUB1) |
| Research Area | Metabolism |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1043-1073 amino acids from the C-terminal region of human BUB1 (BUB1a). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O43683 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PC26, F5GXI5, O43430, O43643, O60626, Q53QE4 |
| UniProt Entry Name | BUB1_HUMAN |
| Gene Symbol | BUB1 |
| GeneID | 699 |
| OMIM | 602452 |
| HGNC | 1148 |
| KEGG | hsa:699 |
| Ensembl | ENSG00000169679 |
| String | 9606.ENSP00000302530 |
| Molecular Weight | Calculated MW: 122 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |