Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 (BUB1) Antibody

BUB1 Antibody is a Rabbit Polyclonal antibody against BUB1. This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

Target	Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 (BUB1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human BUB1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43683 (UniProt, ExPASy)
UniProt Secondary AC	E9PC26, F5GXI5, O43430, O43643, O60626, Q53QE4
UniProt Entry Name	BUB1_HUMAN
Gene Symbol	BUB1
GeneID	699
NCBI Accession	NP_004327.1
KEGG	hsa:699
String	9606.ENSP00000302530
Molecular Weight	Calculated MW: 122 kDa Observed MW: 133 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 (BUB1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue