Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 (BUB1) Antibody
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Catalogue No: abx001575
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US$217.50
(Size: 20 µl)
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Datasheet SDS
BUB1 Antibody is a Rabbit Polyclonal antibody against BUB1. This gene encodes a Serine/Threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
Research Articles on Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 (BUB1)
| Target | Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 (BUB1) |
| Research Area | Metabolism |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to BUB1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O43683 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PC26, F5GXI5, O43430, O43643, O60626, Q53QE4 |
| UniProt Entry Name | BUB1_HUMAN |
| Gene Symbol | BUB1 |
| GeneID | 699 |
| OMIM | 602452 |
| NCBI Accession | NP_004327.1 |
| HGNC | 1148 |
| KEGG | hsa:699 |
| Ensembl | ENSG00000169679 |
| String | 9606.ENSP00000302530 |
| Molecular Weight | Calculated MW: 122 kDa Observed MW: 133 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |