Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 (BUB1) Antibody

Catalogue No: abx001575
Price: £160.00
(Size: 20 µl)
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BUB1 Antibody is a Rabbit Polyclonal antibody against BUB1. This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

Target BUB1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human BUB1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O43683 (UniProt, ExPASy)
UniProt Secondary AC E9PC26, F5GXI5, O43430, O43643, O60626, Q53QE4
UniProt Entry Name BUB1_HUMAN
Gene Symbol BUB1
GeneID 699
KEGG hsa:699
String 9606.ENSP00000302530
Molecular Weight Calculated MW: 115 kDa, 120 kDa, 122 kDa
Observed MW: 133 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on BUB1

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