Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 Beta (BUB1B) Antibody

Catalogue No: abx001472
Price: £120.00
(Size: 20 µl)
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Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 Beta (BUB1B) Antibody Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 Beta (BUB1B) Antibody

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BUB1B Antibody is a Rabbit Polyclonal antibody against BUB1B. This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

Target BUB1B
Clonality Polyclonal
Reactivity Human, Mouse, Rat, Monkey
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human BUB1B.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O60566 (UniProt, ExPASy)
UniProt Entry Name BUB1B_HUMAN
Gene Symbol BUB1B
GeneID 701
KEGG hsa:701
String 9606.ENSP00000287598
Molecular Weight Calculated MW: 105 kDa, 119 kDa, 121 kDa
Observed MW: 60 kDa, 120 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 Beta (BUB1B) Antibody

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