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Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta (BUB1B) Antibody
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Catalogue No: abx001472
Price:
US$348.00
(Size: 60 µl)
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BUB1B Antibody is a Rabbit Polyclonal antibody against BUB1B. This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
Research Articles on Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta (BUB1B)
| Target | Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta (BUB1B) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human BUB1B |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60566 (UniProt, ExPASy) |
| UniProt Entry Name | BUB1B_HUMAN |
| Gene Symbol | BUB1B |
| GeneID | 701 |
| OMIM | 176430 |
| NCBI Accession | NP_001202.4 |
| HGNC | 1149 |
| KEGG | hsa:701 |
| Ensembl | ENSG00000156970 |
| String | 9606.ENSP00000287598 |
| Enzyme Commission Number | EC 2.7.11.1 |
| Molecular Weight | Calculated MW: 105 kDa/119 kDa/121 kDa Observed MW: 55 kDa/120 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
