C-C Motif Chemokine 20 / MIP3A (CCL20) Antibody
REQUEST MORE INFO
Catalogue No: abx239874
Price:
US$420.50
(Size: 100 µg)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
C-C Motif Chemokine 20 / MIP3A (CCL20) Antibody is a Rabbit Polyclonal antibody for the detection of MIP-3α. CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17 (Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells (DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease (COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.
Research Articles on C-C Motif Chemokine 20 / MIP3A (CCL20)
| Target | C-C Motif Chemokine 20 / MIP3A (CCL20) |
| Research Area | Cytokines, Infection Immunity |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Rabbit |
| Recommended dilutions | IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | chemokine (C-C motif) ligand 20 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P78556 (UniProt, ExPASy) |
| UniProt Secondary AC | Q53S51, Q99664 |
| UniProt Entry Name | CCL20_HUMAN |
| Gene Symbol | CCL20 |
| GeneID | 6364 |
| OMIM | 601960 |
| HGNC | 10619 |
| KEGG | hsa:6364 |
| Ensembl | ENSG00000115009 |
| String | 9606.ENSP00000351671 |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |