Mast/stem Cell Growth Factor Receptor Kit (C-Kit) Antibody
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Catalogue No: abx010475
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US$427.75
(Size: 100 µl)
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Datasheet SDS
C-kit (CD117, 145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
Research Articles on Mast/stem Cell Growth Factor Receptor Kit (C-Kit)
| Target | Mast/stem Cell Growth Factor Receptor Kit (C-Kit) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of C-kit expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P10721 (UniProt, ExPASy) |
| UniProt Secondary AC | B5A956, D5LXN2, D5M931, F5H8F8, Q6IQ28, Q99662, Q9UM99 |
| Gene Symbol | KIT |
| GeneID | 3815 |
| OMIM | 154800 |
| HGNC | 6342 |
| Ensembl | ENSG00000157404 |
| Molecular Weight | 145 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |