C4b-Binding Protein Beta Chain (C4BPB) Antibody

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Catalogue No: abx004862
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
C4b-Binding Protein Beta Chain (C4BPB) Antibody is a Rabbit Polyclonal antibody against C4b-Binding Protein Beta Chain (C4BPB). This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.

Target C4b-Binding Protein Beta Chain (C4BPB)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 17-251 of human C4BPB.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P20851 (UniProt, ExPASy)
UniProt Secondary AC A5JYP8, D3DT81, Q5VVR0, Q9BS25
UniProt Entry Name C4BPB_HUMAN
Gene Symbol C4BPB
GeneID 725
OMIM 120831
NCBI Accession NP_001017364.1
HGNC 1328
KEGG hsa:725
Ensembl ENSG00000123843
String 9606.ENSP00000243611
Molecular Weight Calculated MW: 28 kDa
Observed MW: 28 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration 3.32 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on C4b-Binding Protein Beta Chain (C4BPB)


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