Calretinin (CALB2) Antibody

Calretinin (CALB2) Antibody is a Rabbit Polyclonal antibody for the detection of Calretinin.

Calbindin 2 (calretinin), is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Calretinin is a useful marker for differentiating malignant mesothelioma from carcinomas.

Target	Calretinin (CALB2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	calbindin 2
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P22676 (UniProt, ExPASy)
UniProt Secondary AC	A8K4Y1, Q53HD2, Q96BK4
UniProt Entry Name	CALB2_HUMAN
Gene Symbol	CALB2
GeneID	794
OMIM	114051
HGNC	1435
KEGG	hsa:794
Ensembl	ENSG00000172137
String	9606.ENSP00000307508
Molecular Weight	Observed MW: 32 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Calretinin (CALB2)

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