Calcium/Calmodulin Dependent Protein Kinase II Alpha Phospho-Thr305 (CAMK2A pT305) Antibody
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Catalogue No: abx239854
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US$406.00
(Size: 100 µg)
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Datasheet SDS
Calcium/Calmodulin Dependent Protein Kinase II Alpha Phospho-Thr305 (CAMK2A pT305) Antibody is a Rabbit Polyclonal antibody for the detection of Phospho-Camk2a-T286. The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca (2+) /calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM) -dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Research Articles on Calcium/Calmodulin Dependent Protein Kinase II Alpha Phospho-Thr305 (CAMK2A pT305)
| Target | Calcium/Calmodulin Dependent Protein Kinase II Alpha Phospho-Thr305 (CAMK2A pT305) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | calcium/calmodulin-dependent protein kinase II alpha |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9UQM7 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9UL21, Q9Y2H4, Q9Y352 |
| UniProt Entry Name | KCC2A_HUMAN |
| Gene Symbol | CAMK2A |
| GeneID | 815 |
| String | 9606.ENSP00000381412 |
| Enzyme Commission Number | EC 2.7.11.17 |
| Molecular Weight | Observed MW: 54 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |