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Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B (PDE1B) Antibody
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Catalogue No: abx015959
Price:
US$427.75
(Size: 100 µl)
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The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily.Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex.This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate.cAMP and cGMP function as key regulators of many important physiological processes.Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Research Articles on Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B (PDE1B)
| Target | Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B (PDE1B) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PDE1B (AA: 370-536) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q01064 (UniProt, ExPASy) |
| UniProt Secondary AC | Q92825, Q96KP3 |
| Gene Symbol | PDE1B |
| GeneID | 5153 |
| OMIM | 171891 |
| HGNC | 8775 |
| Ensembl | ENSG00000123360 |
| Molecular Weight | 61.4 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |