Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2A) Antibody

CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo or heteromultimeric holoenzymes composed of 8 to 12 subunits.

Target	Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2A)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 446-478 amino acids from the C-terminal region of human CAMK2A (CAMK2 alpha).
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UQM7 (UniProt, ExPASy)
UniProt Secondary AC	Q9UL21, Q9Y2H4, Q9Y352
UniProt Entry Name	KCC2A_HUMAN
String	9606.ENSP00000381412
Molecular Weight	Calculated MW: 54.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rat CAMK2A.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Calcium/Calmodulin Dependent Protein Kinase II Alpha (CAMK2A)

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