Cardiac Troponin T2 (TNNT2) Antibody

Cardiac Troponin T2 (TNNT2) Antibody is a Goat Polyclonal antibody against Cardiac Troponin T2 (TNNT2). The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Target	Cardiac Troponin T2 (TNNT2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Pig
Tested Applications	P-ELISA, WB
Host	Goat
Recommended dilutions	P-ELISA: 1/128000, WB: 0.1-0.3 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Internal region, 201-213 AA: C-TERKSGKRQTERE
Isotype	IgG
Form	Liquid
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P45379 (UniProt, ExPASy)
UniProt Secondary AC	A2TDB9, A8K3K6, O60214, Q99596, Q99597, Q9BUF6, Q9UM96
UniProt Entry Name	TNNT2_HUMAN
Gene Symbol	TNNT2
GeneID	7139 21956 24837
OMIM	115195
NCBI Accession	NP_000355.2 NP_001001430.1 NP_001001431.1 NP_001001432.1
HGNC	11949
Ensembl	ENSG00000118194
String	9606.ENSP00000236918
Buffer	Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Specificity	Predicted to react with Rat, Cat, Dog, and Cow TNNT2 by sequence homology.
Concentration	0.5 mg/ml
Availability	Shipped within 1-3 working days.
Note	This product is for research use only.

Research Articles on Cardiac Troponin T2 (TNNT2)

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