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Troponin T, Cardiac Muscle (TNNT2) Antibody
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Catalogue No: abx011888
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Research Articles on Troponin T, Cardiac Muscle (TNNT2)
| Target | Troponin T, Cardiac Muscle (TNNT2) |
| Research Area | Cardiovascular Biology |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human troponin T2 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P45379 (UniProt, ExPASy) |
| UniProt Secondary AC | A2TDB9, A8K3K6, O60214, Q99596, Q99597, Q9BUF6, Q9UM96 |
| UniProt Entry Name | TNNT2_HUMAN |
| Gene Symbol | TNNT2 |
| GeneID | 7139 |
| OMIM | 115195 |
| NCBI Accession | NP_001001432.1 NM_001001432.2 |
| HGNC | 11949 |
| Ensembl | ENSG00000118194 |
| String | 9606.ENSP00000236918 |
| Molecular Weight | 36 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |