Caspase 6 (CASP6) Antibody

CASP6 Antibody is a Rabbit Polyclonal antibody against CASP6. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.

Target	Caspase 6 (CASP6)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 194-293 of human Caspase-6.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P55212 (UniProt, ExPASy)
UniProt Secondary AC	Q9BQE7
UniProt Entry Name	CASP6_HUMAN
Gene Symbol	CASP6
GeneID	839
NCBI Accession	NP_001217.2
KEGG	hsa:839
String	9606.ENSP00000265164
Molecular Weight	Calculated MW: 33 kDa Observed MW: 35 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Caspase 6 (CASP6)

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