Caspase 9 (CASP9) Antibody

Catalogue No: abx002046
Price: £120.00
(Size: 20 µl)
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Caspase 9 (CASP9) Antibody Caspase 9 (CASP9) Antibody Caspase 9 (CASP9) Antibody Caspase 9 (CASP9) Antibody

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CASP9 Antibody is a Rabbit Polyclonal antibody against CASP9. This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

Target CASP9
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/200 - 1/500, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CASP9.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P55211 (UniProt, ExPASy)
UniProt Entry Name CASP9_HUMAN
Gene Symbol CASP9
GeneID 842
KEGG hsa:842
String 9606.ENSP00000330237
Molecular Weight Calculated MW: 17 kDa, 30 kDa, 36 kDa, 46 kDa
Observed MW: 46 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Caspase 9 (CASP9) Antibody

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