Menu

Caveolin 1 (CAV1) Antibody

Catalogue No: abx000539
Price: £120.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Available Options

* Size:




CAV1 Antibody is a Rabbit Polyclonal antibody against CAV1. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

Target CAV1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human CAV1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q03135 (UniProt, ExPASy)
UniProt Secondary AC Q9UGP1, Q9UNG1, Q9UQH6
UniProt Entry Name CAV1_HUMAN
Gene Symbol CAV1
GeneID 857
String 9606.ENSP00000339191
Molecular Weight Calculated MW: 17 kDa, 20 kDa
Observed MW: 22 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Caveolin 1 (CAV1) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good