Cystathionine Beta-Synthase (CBS) Antibody

CBS Antibody is a Rabbit Polyclonal antibody against CBS. The CBS gene encodes cystathionine beta-synthase, which catalyzes the first irreversible step of transsulfuration. The CBS enzyme is a homotetramer of 63-kD subunits and requires pyridoxal phosphate and heme for activity(PMID:11230183). CBS protein is localized in most areas of the brain, but predominantly in the cell bodies and neuronal processes of Purkinje cells and Ammon's horn neurons(PMID:12588964). This antibody is specific to CBS.

Target	Cystathionine Beta-Synthase (CBS)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human CBS.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35520 (UniProt, ExPASy)
UniProt Secondary AC	B2R993, D3DSK4, Q99425, Q9BWC5
UniProt Entry Name	CBS_HUMAN
Gene Symbol	CBS
GeneID	875
NCBI Accession	NP_000062.1
KEGG	hsa:102724560 hsa:875
Molecular Weight	Calculated MW: 61 kDa Observed MW: 61 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cystathionine Beta-Synthase (CBS)

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