Chromobox Protein Homolog 3 (CBX3) Antibody
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Catalogue No: abx001835
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US$377.00
(Size: 60 µl)
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Datasheet SDS
CBX3 Antibody is a Rabbit Polyclonal antibody against CBX3. At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
Research Articles on Chromobox Protein Homolog 3 (CBX3)
| Target | Chromobox Protein Homolog 3 (CBX3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human CBX3 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q13185 (UniProt, ExPASy) |
| UniProt Secondary AC | Q96CD7, Q99409, Q9BVS3, Q9P0Z6 |
| UniProt Entry Name | CBX3_HUMAN |
| Gene Symbol | CBX3 |
| GeneID | 11335 |
| NCBI Accession | NP_009207.2 |
| KEGG | hsa:11335 |
| String | 9606.ENSP00000336687 |
| Molecular Weight | Calculated MW: 20 kDa Observed MW: 23 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
