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Chromobox Protein Homolog 3 (CBX3) Antibody

Catalogue No: abx001835
Price: £160.00
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Chromobox Protein Homolog 3 (CBX3) Antibody Chromobox Protein Homolog 3 (CBX3) Antibody Chromobox Protein Homolog 3 (CBX3) Antibody Chromobox Protein Homolog 3 (CBX3) Antibody

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CBX3 Antibody is a Rabbit Polyclonal antibody against CBX3. At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

Target CBX3
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human CBX3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13185 (UniProt, ExPASy)
UniProt Secondary AC Q96CD7, Q99409, Q9BVS3, Q9P0Z6
UniProt Entry Name CBX3_HUMAN
Gene Symbol CBX3
GeneID 11335
KEGG hsa:11335
String 9606.ENSP00000336687
Molecular Weight Calculated MW: 20 kDa
Observed MW: 23 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Chromobox Protein Homolog 3 (CBX3) Antibody

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