Chromobox Protein Homolog 5 (CBX5) Antibody
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Catalogue No: abx030865
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins (By similarity).
Research Articles on Chromobox Protein Homolog 5 (CBX5)
| Target | Chromobox Protein Homolog 5 (CBX5) |
| Research Area | Metabolism |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 160-186 amino acids from the C-terminal region of mouse Cbx5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q61686 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9CS35, Q9CXD1 |
| UniProt Entry Name | CBX5_MOUSE |
| KEGG | mmu:12419 |
| String | 10090.ENSMUSP00000113157 |
| Molecular Weight | Calculated MW: 22.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Human Cbx5. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |