Chromobox Protein Homolog 5 (CBX5) Antibody

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Target	Chromobox Protein Homolog 5 (CBX5)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 88-117 amino acids from the Central region of human CBX5.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P45973 (UniProt, ExPASy)
UniProt Secondary AC	B2R8T9
UniProt Entry Name	CBX5_HUMAN
KEGG	hsa:23468
String	9606.ENSP00000209875
Molecular Weight	Calculated MW: 22.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse CBX5.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chromobox Protein Homolog 5 (CBX5)

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