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Coiled-Coil Domain-Containing Protein 99 (CCDC99) Antibody
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Catalogue No: abx027429
Price:
US$326.25
(Size: 80 µl)
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CCDC99 is required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
Research Articles on Coiled-Coil Domain-Containing Protein 99 (CCDC99)
| Target | Coiled-Coil Domain-Containing Protein 99 (CCDC99) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 459-488 amino acids from the C-terminal region of human CCDC99. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96EA4 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E393, C9JS47, Q8TEC8, Q9HD44, Q9NX97 |
| UniProt Entry Name | SPDLY_HUMAN |
| KEGG | hsa:54908 |
| String | 9606.ENSP00000265295 |
| Molecular Weight | Calculated MW: 70.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey SPDL1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |