C-C Motif Chemokine 2 / MCP1 (CCL2) Antibody
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Catalogue No: abx032942
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL2 is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Research Articles on C-C Motif Chemokine 2 / MCP1 (CCL2)
| Target | C-C Motif Chemokine 2 / MCP1 (CCL2) |
| Research Area | Cytokines, Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 62-89 amino acids from the C-terminal region of human CCL2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P13500 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R4V3, Q9UDF3 |
| UniProt Entry Name | CCL2_HUMAN |
| Gene Symbol | CCL2 |
| GeneID | 6347 |
| OMIM | 158105 |
| NCBI Accession | NP_002973.1 NM_002982.3 |
| HGNC | 10618 |
| KEGG | hsa:6347 |
| Ensembl | ENSG00000108691 |
| String | 9606.ENSP00000225831 |
| Molecular Weight | Calculated MW: 11 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey CCL2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |